Ke huhū nei ʻo SARS-CoV-2 (COVID19) a puni ka honua, a ua ʻike ʻia ka lāʻau lapaʻau ʻo ia ke ala ʻoi aku ka maikaʻi a me ka maikaʻi e pale ai i ka maʻi maʻi maʻi.Hoʻohana ka loiloi kuʻuna maʻamau i nā ʻano hana ʻike antibody no ka loiloi i ka pono o nā kano ma o nā hoʻokolohua neutralization;
ʻO nā hana kuʻuna i ka manawa a me ka haʻahaʻa i ka pono, e lawe mau ana i ka 2 a 4 mau lā e hoʻopau ai i ka loiloi, a no ka hoʻohana ʻana o ka hapa nui o lākou i nā maʻi maʻi ola, pono ia e lawe ʻia ma kahi biosafety pae 3 a i luna o ka hale hana, ʻo ia ka manawa- hoopau a hooluhi, a he pilikia nuii ka loiloi o ka hoʻonui a me ka hōʻuluʻulu.No laila, he koi koʻikoʻi no kahi ala maʻalahi a wikiwiki hoʻi i kūpono no ka loiloi ʻana i nā antibodies pale i nā heluna nui.
Hoʻohana ʻia ʻo Aehealth COVID19 Neutralization Antibody Rapid Test Kits no ka ʻike ʻana i nā antibodies neutralination COVID19 i ka serum kanaka, plasma a i ʻole ke koko holoʻokoʻa.Hiki ke hoʻohana ʻia no ka ʻike wikiwiki a paʻakikī loa i ka vitro.hoʻohana maʻi i ka loiloi kōkua o ka hopena o ke kano COVID19 a me ka loiloi o nā antibodies neutralization i nā maʻi i hoʻihoʻi ʻia ma hope o ka maʻi.
Hana maʻalahi
- ʻAʻole pono e aʻo ʻia nā ʻoihana
- Hoʻohālikelike me nā ʻano kikoʻī he nui: Serum/Plasma/Koko holoʻokoʻa/koko piha manamana lima.
ʻoluʻolu
- ʻAʻohe mea hana pono
Pono
- Hoao: 15-20 min;
Hoʻopau maikaʻi nā antibodies neutralization i ka maʻi ma ke kāohi ʻana i ka pilina ma waena o ka maʻi maʻi COVID19 a me nā cell host.ʻO ka hapa nui o nā antibodies neutralization e pane i ka receptor binding domain (RBD) o ka spike protein, e hoʻopili pololei ana i ka cell surface receptor ACE2.Ke hāʻawi nei nā antibodies-online i ʻelua mau antibodies neutralization e pili ana i ka clone CR3022.ʻOiai ʻo ka hapa nui o nā antibodies S-protein RBD hoʻopaʻa i ka antigen paʻa me ACE2, ʻaʻole e uhi ka epitope CR3022 me ka pūnaewele paʻa ACE2.
No laila ʻaʻole ia e pale i ka hoʻopaʻa ʻana o nā antibodies neutralization.ʻOiai ʻo CR3022 ma kāna iho hōʻike wale i kahi hopena neutralization nāwaliwali, ua hōʻike ʻia e synergize me nā antibodies paʻa S-protein RBD e pale i ka COVID19.
