Nā ʻano hana
Ka palena ʻike: 0.08ng/mL ;
Laina Linear: 0.08~10.00 ng/mL;
Koefficient huikau laina R ≥0.990;
Ka pololei: i loko o ka puʻupuʻu CV ʻo ≤15%;ma waena o nā pūʻulu CV he ≤20%;
Pono: ʻaʻole e ʻoi aku ka ʻae ʻana o nā hopena ana ma mua o ± 15% ke hoʻāʻo ʻia ka calibrator pololei.
1. E mālama i ka mea ʻike maka ma 2~30 ℃.Kūpaʻa ka buffer a hiki i 18 mahina.
2. E kūʻai i ka cassette hōʻike Aehealth Ferritin Rapid Quantitative ma 2~30 ℃, a hiki i ka 18 mahina.
3. Pono e hoʻohana i ka pahu hoʻāʻo i loko o 1 hola ma hope o ka wehe ʻana i ka ʻeke.
Ua ʻike ʻia ka protein S100 i loko o ka lolo pipi e Moore BW i ka makahiki 1965. Ua kapa ʻia ʻo ia ma hope o ka hiki ke hoʻoheheʻe ʻia ka protein i 100% ammonium sulfate.ʻElua mau subunits α a me β i hui ʻia e hana i S100αα, S100αβ, a me S100-ββ.Ma waena o lākou, ua kapa ʻia ʻo S100-β (S100αβ a me S100-ββ) protein i ke kikowaena nerve-specific protein, a ua wehewehe kekahi poʻe loea ʻo ia ka "C-reactive protein" o ka lolo.ʻO ka ʻakika calcium-binding protein me ke kaumaha molekala o 21KD ka mea i hana nui ʻia e nā astrocytes., Ma o ka hoʻokumuʻiaʻana o nā paʻa disulfide e nā koena o ka cysteine, aia ia i loko o ke kikowaena pūnaewele ma kahi nui ma keʻano o ka hana dimer.
Loaʻa i ka protein S100-β ka nui o nā hana olaola a he koʻikoʻi koʻikoʻi i ka hoʻonui ʻana o ka cell, ka ʻokoʻa, ka hōʻike gene, a me ka apoptosis cell.Ma lalo o nā kūlana physiological, hōʻike nāwaliwali ka protein S100-β i loko o ka lolo i ka lā 14 o ka wā embryonic, a laila hoʻonui i ka like me ka ulu a me ka ulu ʻana o ka ʻōnaehana nerve, a paʻa i ka wā makua.ʻO ka protein S100-β kahi mea neurotrophic i ke kūlana physiological, e pili ana i ka uluʻana, ka hoʻonui a me ka hoʻokaʻawaleʻana o nā pūnaewele glial, mālama i ka homeostasis calcium, a hoʻokani i kekahi kuleana i ke aʻoʻana a me ka hoʻomanaʻo, a hoʻoikaika i ka uluʻana o ka lolo;ke loaʻa i nā kānaka nā maʻi noʻonoʻo ʻO ka maʻi, ʻeha lolo (cerebral infarction, brain injury, brain injury after cardiac surgery, etc.) or nerve injury, S100-β protein leaks from cytosol into the cerebrospinal fluid, a laila komo i ke koko ma o ka mea i poino. pale koko-lolo, no laila ke alakaʻi nei kēia i ka hoʻonui ʻana i ka ʻike o ka protein S100-β i ke koko.
Ma ke ʻano he hōʻailona biochemical o ka ʻeha lolo, S100-βʻO ka protein kekahi ʻano hoʻololi manawa ma hope o ka hōʻeha ʻana i ka lolo, a pili loa ia i ke ʻano o ka ʻeha o ka lolo a me ka prognosis, a he kūpaʻa maikaʻi.He mea kōkua ka ʻike ʻana i kona waiwai no ka hoʻoponopono ʻana i nā aʻalolo.ʻO ka nui o ka lesion tissue, ka hopena lapaʻau a me ka prognosis o ke kanaka.