Nā ʻano hana
Ka palena ʻike:
CK-MB: 2.0 ng/mL;cTnI: 0.1 ng/mL;Myo: 10.0 ng/mL.
Laulā laina:
CK-MB: 2.0-100.0 ng/mL;cTnI: 0.1-50.0 ng/mL;Myo: 10.0-400.0 ng/mL.
Koefficient huikau laina R ≥ 0.990;
Ka pololei: i loko o ka puʻupuʻu CV ʻo ≤ 15%;ma waena o nā pūʻulu CV he ≤ 20%;
Pono: ʻaʻole e oi aku ka haʻihaʻi pili o nā hopena ana i ka ±15% ke hoʻāʻo ʻia ka calibrator pololei.
1. E mālama i ka mea ʻike maka ma 2~30 ℃.Kūpaʻa ka buffer a hiki i 18 mahina.
2. E kūʻai i ka cassette hōʻike Aehealth Ferritin Rapid Quantitative ma 2~30 ℃, a hiki i ka 18 mahina.
3. Pono e hoʻohana i ka pahu hoʻāʻo i loko o 1 hola ma hope o ka wehe ʻana i ka ʻeke.
Hoʻokumu ʻia ʻo Troponin I he 205 amino acids me ka weiaht molecular pili ma kahi o 24KD.He protein waiwai i ka alpha helix;hana ia i mea paʻakikī me cTnT a me cTnc, a me na mea ekolu i ko lakou ano iho a me ka hana. Ma hope o ka myocardial hōʻeha i loko o kanaka, myocardial pūnaewele rupture, a me ka troponin I ua hoʻokuʻu 'ia i loko o ke koko circulatory nenoaiu, e piʻi nui i loko o 4 a 8 hola. hiki i ka waiwai kiʻekiʻe ma 12 a 16 mau hola ma hope o ka hōʻeha myocardial, a mālama i kahi waiwai kiʻekiʻe no 5 a 9 mau lā.
Troponin I loaʻa i kahi kiʻekiʻe o ka myocardial specificity a me ka sensitivity, a i kēia manawa ka manaʻo biomarker o ka myocardial infarction.
ʻEhā ʻano isoenzyme ʻo Creatine Kinase (CK): ʻano ʻiʻo (MM), ʻano lolo (BB), ʻano hybrid (MB) ʻano mitochondrial ʻano (MiMi).Aia ka Creatine kinase i loko o nā ʻiʻo he nui, akā ʻokoʻa ka māhele ʻana o kēlā me kēia isoenzyme.Nui ka ʻiʻo iwi i nā isoenzymes M-type, ʻoiai ʻo ka lolo, ka ʻōpū, ka ʻōpū liʻiliʻi a me ka lunas ka nui o nā isoenzymes B-type.ʻO nā isoenzymes MB ma kahi o 15% a 20% o ka nui o CK, a aia wale lākou i loko o ka ʻiʻo myocardial.ʻO kēia hiʻohiʻona e lilo ia i waiwai diagnostic, e hoʻolilo iā ia i mea hoʻailona enzyme waiwai nui no ka hoʻomaʻamaʻa ʻana i nā mea ʻeha myocardial.ʻO ka loaʻa ʻana o CK-MB i loko o ke koko e hōʻike ana i ka pōʻino o ka myocardial.He mea koʻikoʻi ka nānā ʻana o CK-MB no ka ʻike ʻana i ka myocardial ischemia
ʻO ka Myoglobin (Myoglobin, Myo) he pūmua paʻa i haku ʻia me ke kaulahao peptide a me ka qroup prosthetic heme He pūmua ia e mālama ai i ka oxygen i loko o ka ʻiʻo.He liʻiliʻi kona kaumaha molekala, ma kahi o 17,800 Daltons, hiki ke wikiwiki loa Ua hoʻokuʻu koke ʻia ia mai ka ʻiʻo myocardial ischemic, no laila he hōʻailona maikaʻi maikaʻi loa ia o ka ʻeha myocardial ischemic, a ʻo ka hopena maikaʻi ʻole o kēia hōʻailona he mea kōkua nui ia e hoʻokuʻu i ka myocardial infarction, a hiki i kāna waiwai wānana maikaʻi ke hiki i 100%.ʻO ka myoglobin ka protein non-enzymatic mua i hoʻohana ʻia e ʻike i ka ʻeha myocardial.He mea koʻikoʻi koʻikoʻi akā ʻaʻole ia he kuhikuhi diagnostic kikoʻī a he mākaʻikaʻi hoʻi a wikiwiki hoʻi no ka hoʻopaʻa hou ʻana ma hope o ka recanalization coronary.