ʻO ka World Arthritis Day he hanana hoʻonaʻauao olakino honua i hoʻonohonoho ʻia i kēlā me kēia makahiki ma ka lā 12 ʻOkakopa e hoʻokumu i ka ʻike e pili ana i nā maʻi rumatika a me nā maʻi musculoskeletal, kona hopena i ke ola o kekahi a me ka hoʻonaʻauao ʻana i nā kānaka i nā hōʻailona a me nā hana pale a alakaʻi i ka ʻike mua e hoʻokō i nā pilikia hou aʻe. .
Koʻikoʻi o ka World Arthritis Day (WAD)
ʻO ka Arthritis kahi maʻi ʻāʻī, e pili ana i nā ʻiʻo ami a puni ka hui, a me nā ʻiʻo pili ʻē aʻe, e hoʻoulu ai i ka ʻeha a me ka ʻoʻoleʻa.ʻOi aku ma mua o 100 mau ʻano o ka maʻi ʻāʻī, akā ʻo ka mea maʻamau ʻo ka osteoarthritis a me ka rheumatoid arthritis.Ma muli o ka nele o ka ʻike a me ke kākoʻo ʻana, ʻo ka maʻi ʻāʻī a me kona ʻano pili i hoʻopōʻino i ke ola a puni ka honua.ʻAʻohe lāʻau lapaʻau kūikawā no ka maʻi arthritis, ʻokoʻa ke koho lapaʻau e pili ana i nā ʻano, no laila pono e hoʻomaopopo i ka hōʻailona a me nā hōʻailona a loaʻa i ka maʻi maʻi mua e loaʻa ai ka lāʻau kūpono.
ʻO ke ʻano maʻamau o ka Arthritis
ʻO nā ʻano maʻamau ka osteoarthritis (OA), rheumatoid arthritis (RA), psoriatic arthritis (PsA), fibromyalgia a me ka gout.Hiki i nā maʻi ʻeha a me nā maʻi pili ke hoʻonāwaliwali i ka ʻeha e hoʻololi i ke ola ma nā ʻano like ʻole.
ʻO ka Rheumatoid Arthritis (RA) kekahi o nā maʻi maʻamau maʻamau, ʻoi aku ka maʻamau o nā wahine waena.Hōʻike nui ʻia e like me ka polyarthritis maʻi, symmetrical, holomua.Ma waho aʻe o ka hoʻopili ʻana i nā ami, nui nā hōʻike extra-articular, e like me ka ʻili, ka maka, ka puʻuwai, ka māmā, ka ʻōnaehana koko, etc.
ʻO ka prevalence o RA he 0.5-1%, me ka ratio o ka wahine me ke kāne o 3: 1.ʻO 4 a 5 mau manawa kiʻekiʻe i nā wahine ma lalo o 50 mau makahiki, akā ma hope o 60 mau makahiki e lilo ka ratio ma kahi o 2 a 1.Loaʻa pinepine ka poʻe me ka maʻi rumatika i kahi kiʻekiʻe C-reactive protein (CRP) kiʻekiʻe, e hōʻike ana i ka loaʻa ʻana o kahi kaʻina inflammatory i loko o ke kino.ʻO nā hoʻāʻo koko maʻamau ʻē aʻe e nānā i nā mea ʻeleʻele o ka rheumatoid factor (RF) a me ka anti-cyclic citrullinated peptide (anti-CCP).
RA(Rheumatoid arthritis)
ʻO ka maʻi Rheumatoid kahi maʻi ʻeha mau loa e hiki ke hoʻopilikia i nā mea ʻoi aku ma mua o kou mau ami.I kekahi poʻe, hiki i kēia maʻi ke hōʻino i nā ʻōnaehana kino like ʻole, e like me ka ʻili, ka maka, ka māmā, ka puʻuwai a me nā kīʻaha koko.
ʻO kahi maʻi autoimmune, ʻo ka rheumatoid arthritis ka wā e hoʻouka hewa ai kāu ʻōnaehana pale i nā ʻiʻo o kou kino ponoʻī.
ʻAʻole like me ka hōʻino ʻana o ka osteoarthritis, ʻo ka rumatika rheumatoid e pili ana i ka ʻili o kou mau ami, e hoʻoulu ai i ka ʻeha ʻeha e hiki ai ke hoʻoheheʻe ʻia ka iwi a me ka deformity hui.
Anti-CCP Anti-Cyclic Citrullinated Peptide Antibody
Anti-cyclic citrullinated peptide antibody (Anti-CCP): He ʻāpana polypeptide ia o ka protein polyguanidine cyclic a ʻo ia ka antibody ʻano IgG.ʻO nā anti-cyclic citrullinated peptide antibodies i huna ʻia e nā lymphocytes B o nā maʻi me ka rheumatoid arthritis (RA), ʻoiai ʻo nā lymphocytes B o nā maʻi me nā maʻi ʻē aʻe a me nā kānaka maʻamau ʻaʻole i hūnā i nā anti-cyclic citrullinated peptide antibodies.No laila, he kiʻekiʻe kona naʻau a me ka kikoʻī no ka rheumatoid arthritis, a he hōʻailona kikoʻī loa ia no ka ʻike mua ʻana o ka maʻi rumatika.
ʻO ka Anti-CCP (Anti-cyclic citrullinated peptides) he ʻano autoantibody: he antibody e hana kūʻē i nā antibodies maʻamau o kou kino.Hoʻopuka pinepine ʻia ka Anti-CCP inā loaʻa iā ʻoe ka rheumatoid arthritis.Hoʻomaka kēia mau autoantibodies i ka huli ʻana a hoʻouka i nā ʻiʻo olakino ʻē aʻe.
Nā hōʻailona hōʻailona mua o ka maʻi rumatika: ʻike ʻia nā antibodies anti-cyclic citrullinated 1-10 mau makahiki ma mua o ka hōʻike ʻana o ka maʻi rheumatoid arthritis, kūpono no ka nānā kino ʻana i nā kānaka olakino a me ka ʻike mua ʻana o nā pūʻulu pilikia.I kēia manawa,ua manaʻo ʻia ʻo ka sensitivity o anti-cyclic citrullinated peptide antibodies no ka hōʻoia ʻana o ka rheumatoid arthritis he 50% a 78%, ʻo 96% ka kikoʻī, a hiki i ka helu maikaʻi o nā maʻi mua ke hiki i 80%.
Aeheola kinoAnti-CCP Plāʻau lāʻau
Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Ho'āʻo Rapid Quantitative Hoʻoholo i ke ʻano Immunofluorescence Assay.
He 10～500 U/mL ka laina laina ʻike kit Anti-CCP;hiki ke hiki i ka huina hooponopono laina ma waena o ka manaʻo kuʻuna a me ke ana i ka r≥0.990.Hoʻohana ʻia ia me ka loiloi immunofluorescence Aehealth Lamuno X e alakaʻi i ka ʻike mua a me ka loiloi lapaʻau o nā maʻi rumatika.
Hoʻopili nā anti-CCP antibodies me nā ʻāpana hana RA.
Manaʻo nā anti-CCP antibodies i ka pōʻino RA.
Ka manawa hoʻouna: Oct-12-2022